Hi there. I'm completely car stupid, but I know a few things. I have an 05 Civic ex and I keep getting codes for multiple misfires and all 4 cylinders misfired. Replaced spark plugs, same codes. Only physical symptoms of car is a little hesitant when accelerating from a stop and hesitation at high speed. 50-70 mph. That's when the cel comes on. Any ideas?

pressure test the fuel pump AFTER changing the fuel filter. Clogged filter or weak pump often do that

That's exactly what I was thinking, but I wanted to check with a true expert first and gather your opinion. I watch the videos and love them. Thank you so much! Fuel filter gonna be a pain on this civic!